• For beautiful and clear skin.
  • Freedom from Melasma with UV protection whitening effect.


Skin pigmentation is most common in women, with about 10% of cases reported in men. It affects people of any race but is more prominent among Asians and Latinos, those living in areas of high UV light exposure.

Clinically speaking, pigmentation can be divided into three patterns. In centrofacial pattern, the pigmentation occurs on the cheeks, forehead, upper lip, nose and chin. In malar pattern the patches appear on the cheeks and nose, while in mandibular pattern they show on the side of the cheeks and jaw line.

Types of pigmentation include epidermal pigmentation where the pigmentation resides in the epidermis layer of the skin, dermal pigmentation where the pigmentation is located in the dermis layer, and mixed pigmentation, a mixture of epidermal and dermal types. Epidermal pigmentation is the most common type and relatively more responsive to treatments..

Pycnogenol: Hyper pigmentation:

in a clinical trial of 30 women with this condition, Pycnogenol® supplementation at 75mg/day significantly lightened their excess skin pigmentation.



as skin whitener,its skin whitening regimen has been widely used in Asia and has been reported to be the Asian Most Prescribed Topically Skin Whitener among the skin whitening products.There is no question at all because it’s already been proven that L-Glutathione is really effective in whitening the skin for it works by reducing the melanin formation safely. There are several L-Glutathione preparations in the market but not all can really guarantee a good result.


 Paper Mulberry extract, is obtained from the root of Broussonetia kazinoki, Siebold. or B. papyrifera, Vent. Tabl. Regn. Veget. Or hybrids of both, family Moraceae. Extracts of this root are potent inhibitors of Tyrosinase enzyme. The active constituents present in the extract are Prenylated, polyhydroxylated mono-and bis-phenylderivatives. A 0.4% concentration of paper mulberry extract inhibits tyrosinase by 50% compared to 5.5% for hydroquinone and 10.0% for kojic acid. At 1% paper mulberry extract is not a significant irritant.


is the main ingredient of the most popular cosmeceutical used for hyper pigmentation in the Indian market, that is fair and Lovely fairness cream where it is combined with sunscreen for additional benefits [Table 1]. In another variety of the same product, niacinamide is used along with Vitamin C.


A form of vitamin B3 that acts like soy by inhibiting the transfer of melanosomes into the skin’s upper layer.Used in many cosmeceuticals for its skin lightening effects and its potential to prevent additional pigment from coming to the surface of the skin.

28. Hakozaki T, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, et al. The effect of niacinamide on reducing                                     cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol. 2002; 147:20–31. [PubMed]


TOXICITY:No toxicities have been reported or suspected as being associated with glutathione.

None known, except for use during some forms of chemotherapy and radiation where antioxidants are contraindicated due to their inhibition of the free radical formation which is an integral part of the therapeutic mechanism.

One capsule daily.                                                                                                                                  PRECAUTION:

Pregnant & Brest feeding mothers do not use.


Dann Mef available 30’s in Pack.
Marketed by: Dann Health & Skincare(Pvt)ltd.


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